SkinCeuticals A.G.E. Interrupter Advanced
SkinCeuticals A.G.E. Interrupter Advanced
SkinCeuticals A.G.E. Interrupter Advanced
SkinCeuticals A.G.E. Interrupter Advanced
SkinCeuticals A.G.E. Interrupter Advanced
SkinCeuticals A.G.E. Interrupter Advanced
SkinCeuticals A.G.E. Interrupter Advanced
SkinCeuticals A.G.E. Interrupter Advanced
SkinCeuticals A.G.E. Interrupter Advanced
SkinCeuticals A.G.E. Interrupter Advanced


SkinCeuticals A.G.E. Interrupter Advanced

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SkinCeuticals A.G.E. Interrupter Advanced is a corrective anti-aging cream that specifically targets the appearance of advanced glycation end product-related signs of aging, such as wrinkles, loss of skin firmness, and lackluster complexion.

SkinCeuticals A.G.E. Interrupter Advanced is a corrective anti-ageing cream that helps target visible signs of ageing caused by advanced glycation end products (A.G.E), including wrinkles, skin firmness and dullness This advanced anti-aging cream is specially formulated to combat the visible signs of aging caused by advanced glycation end products, resulting in smoother, firmer, and more radiant skin. It's designed to improve the appearance of wrinkles, sagging skin, and dull complexion, making your skin look and feel visibly younger.

SkinCeuticals A.G.E. Interrupter Advanced is suitable for dry, normal, combination, sensitive and ageing skin types.

SkinCeuticals A.G.E. Interrupter is not suitable for use during pregnancy or when breastfeeding.


SkinCeuticals A.G.E. Interrupter Advanced is an effective solution designed to address visible signs of ageing caused by the decline of collagen and glycation. These include wrinkles, sagging, and dullness, which can be influenced by a multi-phase process of excess sugar binding to skin proteins. As key components of youthful-looking skin, it's important to understand the impact of collagen and elastin on the ageing process.

Exposure to UV rays, pollution, and poor diet can lead to oxidative stress, which triggers a reaction that turns bound proteins into A.G.E.s—advanced glycation end-products. A.G.E.s cause proteins to become brittle, resulting in a loss of their regenerative abilities. Since these damaged proteins cannot be replaced, skin becomes weakened, leading to visible signs of ageing such as wrinkles.
A.G.E. Interrupter Advanced is a powerful anti-wrinkle cream designed to address signs of aging caused by collagen breakdown. Its potent formula contains a high concentration of Proxylane, wild fruit flavonoids, glycyrrhetinic acid, HEPES, and niacinamide, effectively correcting wrinkles, loss of firmness, and dullness. Experience the luxurious texture and visible results with this advanced formula.

Collagen and elastin are crucial for maintaining skin's youthful appearance. Though various factors contribute to aging, the binding of excess sugar to these proteins (known as glycation) is a significant factor. Our advanced anti-wrinkle cream features a 12.6% concentration of Proxylane (20% higher than before), a blend of wild fruit flavonoids, and new glycyrrhetinic acid. Made with cutting-edge technology, this cream works to reduce wrinkles, restore skin's firmness, and enhance radiance, resulting in a 38% decrease in collagen damage. In a study, 12 participants received daily treatment with key active flavonoids for 6 days and had their skin analyzed on day 7 following exposure to UVA. Formerly known as A.G.E Interrupter, the product has been reformulated with an improved formula. Read on for more information about the new and improved A.G.E Interrupter Advanced.

SkinCeuticals A.G.E. Interrupter Advanced Benefits:

  • Helps address the multi-phase glycation process known to visibly age skin
  • Smooths an extended range of visible wrinkle types, including fine lines, deep wrinkles, and location-specific creases like nasolabial folds
  • Helps restore skins firmness and elasticity, which is known to decline as glycation degrades skin's collagen
  • Enhances skin's overall radiance, improves tone, and reduces blotchiness for a healthier-looking complexion
  • Delivers rich hydration, with a luxurious, satin finish
  • Free of parabens, drying alcohol, and dyes


Key Ingredients 

12.6% Concentrated Proxylane (new form 20% more concentrated): Key active ingredient in formulas targeting the appearance of wrinkles & laxity. 
4.25% Wild Fruit Flavonoids Combination of blueberry and pomegranate extracts
. 1% glycyrrhetinic acid Liquorice root extract used in formulas for its soothing properties
. 3% HEPES Known to activate natural enzymes in skin to promote even cell turnover while hydrating skin.
 1% Niacinamide Water-soluble vitamin, also known as vitamin b3, used in soothing formulas to help support skin’s moisture barrier. Helps restore skins firmness and elasticity, which is known to decline as glycation degrades skin's collagen.

Aqua / Water, Hydroxypropyl Tetrahydropyrantriol, Glycerin, Propylene Glycol, Stearic Acid, Butyrospermum Parkii Butter / Shea Butter, Hydroxyethylpiperazine Ethane Sulfonic Acid, Palmitic Acid, Pentylene Glycol, Oleyl Alcohol, Arachidyl Alcohol, Myristyl Myristate, Panthenol, Niacinamide, Dimethicone, Isononyl Isononanoate, Bis-peg/ppg-16/16 Peg/ppg-16/16 Dimethicone, Glyceryl Stearate, Candelilla Cera / Candelilla Wax, Behenyl Alcohol, Peg-100 Stearate, Sodium Polyacrylate, Pentaerythrityl Tetraisostearate, 4-t-butylcyclohexanol, Arachidyl Glucoside, Caprylyl Glycol, Xanthan Gum, Chlorphenesin, Myristic Acid, Caprylic/capric Triglyceride, Glycyrrhetinic Acid, Parfum / Fragrance, Sorbitol, Vaccinium Myrtillus Fruit Extract, Potassium Hydroxide, Adenosine, Citric Acid, Punica Granatum Fruit Extract, Limonene, Coumarin, Linalool, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate.

Please note that from time to time, products are innovated without notice. For the most accurate information please consult the product box. 

If you spot an error, please let us know! We will update this ingredients list as soon as possible.


Twice daily, massage a thin, even layer of A.G.E. Interrupter Advanced wrinkle cream onto the entire face, neck, and chest. If using in the morning, apply after a SkinCeuticals vitamin C antioxidant serum and before a SkinCeuticals sunscreen. If using with a retinol at night, apply after retinol application.

If this product is sealed, please ensure the seal is intact prior to using the product.


All Orders Same Day Dispatch by 2pm M-F (Sydney Business Days) any orders placed after 2pm will leave the following (Sydney Business Day). Please note during big sale periods this can be delayed by a day or two.

FREE for orders $49+ via Australia Post e-Parcel road. Express Post Air add $6.95 via Australia Post

Any orders under $49 will have two options for shipping $4.95 e-Parcel post standard shipping by road via Australia post or $9.95 Express Post express shipping by air via Australia post.

If it's not right and you haven't opened it yet, you are welcome to Return It within 30 days. Reach out to our team for authorisation prior to returning to us in original sealed condition.

Already opened or used the product? We can only accept returns if product is faulty, not if you dislike the product! please reach out to us first and we can discuss your options as each brand is different. We can help you understand if a return is possible.

We unfortunately cannot accept returns without return authorisation prior to sending to us.

Customer Reviews

Based on 7 reviews
Trilby shaw
SkinCeuticals A.G .E interrupter

Great feel to this product and it goes a long way.
Only just started using but I have faith.
Would love to buy more in the range

Jessica Brook
Excellent product

Light weight and smells pleasant.
I have been using for about 3 weeks and I have already seen improvement in my fine lines especially around my eyes and smile lines.

Shirley Gu

SkinCeuticals A.G.E. Interrupter Advanced 48ml

jijin bo
perfect texture

Been using age creme for 2 years now, the outcome is truly amazing and

Catherine Hyams
the ultimate age interrupter

SkinCeuticals create phenomenal products - the A.G.E. Interrupter Advanced does just that, whether it's used on it's own or with other SkinCeuticals products.

A little goes a very long way which makes this a good investment