SkinCeuticals Blemish + Age Defense Serum 30ml
SkinCeuticals Blemish + Age Defense Serum 30ml


SkinCeuticals Blemish + Age Defense Serum 30ml

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Blemish + Age Defence is a targeted, oil-free approach for ageing skin prone to breakouts. This acid blend combines 2% dioic acid with an optimal alpha- and beta-hydroxy acid formulation to reduce the formation of acne and clogged pores, while improving the appearance of fine lines, wrinkles, and uneven skin tone.

How does SkinCeuticals Blemish + Age Defense Serum tackle adult acne differently to teenage acne?
Acne is a significant concern on its own, but when acne meets aging, skin damage is magnified. When adults are battling acne, they have a unique set of age-related concerns: Firstly, overactive sebaceous glands results in enlarged pores, secondly, the skin’s texture becomes rough, thirdly, post-inflammatory hyperpigmentation can linger long after blemishes subside. Common stereotypes portray acne as the bane of the teenager: oily, blemished skin, exacerbated by overactive sebaceous glands, adolescent hormones, and less-than-ideal skincare routines. While adolescence is, indeed, a prime time for problematic skin, acne can persist into adulthood. In fact, acne affects 25% of adult men and 50% of adult women.


As an anti-ageing serum and blemish serum in one, Blemish and Age Defense is a powerful formula acne-prone skin. Our formula of LHA, Glycolic Acid, Citric Acid, Dioic Acid and Salicylic Acid is a unique combination. This highly efficacious combination targets excess oil and blemish prone skin. As an anti-ageing serum, these ingredients also target rough skin, fine lines and wrinkles.

Clinical results were seen as early as day 2, with Blemish + AGE Defence significantly reducing inflammatory and non-inflammatory lesions.
Additionally, Blemish + AGE Defence also reduced blotchiness and clogged pores for the entire duration of the 8 week study. (Baumann, L. Comparison of clindamycin 1% and benzoyl peroxide 5% gel to a novel composition containing salicylic acid, capryloyl salicylic acid, HEPES, glycolic acid, citric acid, and dioic acid in the treatment of acne vulgaris - JDD - 2O13).

Blemish + AGE Defence was proven as effective and tolerable as 0.025% tretinoin in both anti-ageing and anti-acne attributes - B+AGE produced statistically superior improvements in skin tone, evenness and clarity, and a reduction in blemishes and blotchiness.

As early as day 2, B+AGE provided improvements in skin tone evenness and clarity, skin smoothness, skin brightness, clogged pores, blemishes, and blotchiness. Parity was achieved between the two treatments in reduction of fine lines, clogged pores, tactile roughness, and dullness.

At no point during the 8-week study did 0.025% tretinoin statistically outperform B+AGE. (Kircik, L. Safety and efficacy of two anti-acne/anti-ageing treatments in subjects with photodamaged skin and mild to moderate acne vulgaris - JDD - 2012).

After 4 weeks, Blemish + AGE Defence was proven to statistically reduce the grade of PIH by 19%.

After 8 weeks, it was proven to reduce the grade of PIH by 36% and the number of PIH marks by 29%.
(Protocol: 8-week dermatologist controlled study consisted of 59 subjects. The subject group consisted of males and females of multi-ethnicities, between the ages of 18-40 with skin types II-V that included mild acne and combination to oily skins, with at least 50% experiencing post-inflammatory hyperpigmentation).


  • Reduces excess sebum production
  • Improves the appearance of blotchiness, blemishes, and uneven skin tone
  • Decongests clogged pores
  • Diminishes visible signs of ageing
  • Ideal for acne-prone, oily, combination, and ageing skin types


Suitable for acne-prone, oily, combination, and ageing skin types.

SkinCeuticals Blemish + AGE Defence is not suitable for use during pregnancy or when breastfeeding.


2% Dioic acid reduces sebum production, fights acne-causing bacteria, and reduces post-inflammatory discolouration

0.3% Capryloyl salicylic acid provides precise and even cell-by-cell exfoliation to decongest clogged pores

1.5% Salicylic acid refines pores and helps reduce acne

3.5% Glycolic acid & 0.5% citric acids accelerate exfoliation


855061 5 - Alcohol Denat., Aqua/ Water, Methylpropanediol, Glycolic Acid, Diisopropyl Adipate, Octadecenedioic Acid, Salicylic Acid, Hydroxyethylpiperazine Ethane Sulfonic Acid, Citric Acid, Capryloyl Salicylic Acid, Sodium Hydroxide, Polyquaternium-10, D43561/3.

Please note that from time to time, products are innovated without notice. For the most accurate information please consult the product box. 

If you spot an error, please let us know! We will update this ingredients list as soon as possible.


Once or twice daily, apply 4-5 drops of Blemish + Age Defense to a dry face.

If this product is sealed, please ensure the seal is intact prior to using the product. 

Customer Reviews

Based on 3 reviews
Kailah Ng
Life changing

This product has changed my skin drastically. I’m in awe. This is now a staple in my routine. My skin is clearer and youthful. When I do have blemishes they come up so differently than they used too.

Sharni Maher

Love my blemish and age defence serum. Removes unwanted hormonal acne

Emily Aiga

Amazing 🤩