iS Clinical Essentials ABC Trio
iS Clinical Essentials ABC Trio
iS Clinical Essentials ABC Trio
iS Clinical Essentials ABC Trio
iS Clinical Essentials ABC Trio
iS Clinical Essentials ABC Trio
iS Clinical Essentials ABC Trio
iS Clinical Essentials ABC Trio

iS Clinical

iS Clinical Essentials ABC Trio

Sale price$669.00

Or 4 interest-free payments

Zip it now, pay later

4 interest-free payments


Transform your complexion with iS Clinical Essentials ABC Trio - a powerful skincare collection that utilises essential vitamins to effectively retexturise and brighten skin. Combat signs of ageing, including fine lines, wrinkles, uneven skin tone, and pigmentation, with this advanced and illuminating formula. This collection includes:

Retinol+ Emulsion 0.3 30ml
Poly-Vitamin Serum 30ml
GeneXC Serum 30ml

Enhance your complexion with iS Clinical Essentials ABC Trio, a collection of advanced skincare formulated with essential vitamins to help retexturise and illuminate skin. Transform your complexion and combat the visible signs of ageing such as fine lines and wrinkles, uneven skin tone, loss of firmness and pigmentation. Achieve a clearer and brighter complexion with iS Clinical Essentials ABC Trio. Developed by skincare professionals and fortified with essential vitamins, witness a transformation in your skin. Minimise fine lines, wrinkles, uneven skin tone, loss of firmness, and pigmentation with this advanced skincare bundle, curated by our head Dermal Therapist at CSH.

iS Clinical Essentials ABC Trio is suitable for all skin types, especially ageing skins, pigmentation, dullness, dehydrated or dry conditions.

iS Clinical Essentials ABC Trio is suitable during pregnancy or when breastfeeding and cancer patients. 


iS Clinical Essentials ABC Trio is the ultimate skin management bundled system containing three key products with essential Vitamins and powerful Antioxidants that work simultaneously to treat common skin conditions and concerns. Retinol Emulsion 0.3, Poly-Vitamin Serum, GeneXC Serum is an expertly crafted skin management system, designed with essential vitamins and potent antioxidants to effectively treat and improve common skin conditions and concerns. With key ingredients such as Extremozyme® technology, Retinol (Vitamin A), Hyaluronic Acid, Vitamin B3 and B5 (Vitamin B), 20% L-Ascorbic Acid (Vitamin C) botanical enzymes and antioxidants, this ttrio provides a scientifically proven approach to healthier, more radiant, youthful skin.

iS Clinical Essentials ABC Trio benefits:

  • Smoothing and balancing
  • Provides the fantastic benefits of vitamins A, B and C
  • Anti-ageing, refine and exfoliate 
  • Cellular turnover 
  • Hydrating and nourishing
  • Gives the look of healthier, more vibrant skin
  • Improves the appearance of skin’s tone and elasticity
  • Helps revitalise the appearance of ageing and compromised skin
  • Enhanced the appearance of skin elasticity and firmness
  • Superior antioxidant protection, Helps provide antioxidant protection to defend against oxidative stressors
  • Helps improve overall health and integrity of the skin
  • Brightening
  • Helps reduce the appearance of fine lines and deep wrinkles
  • Helps diminish the appearance of uneven skin tone, texture, and blemishes
  • Helps protect from environmental stressors with Extremozyme® technology
  • Helps smooth, soften, and brighten complexion
  • Helps to increase the appearance of skin firmness and elasticity
  • Paraben-free


Key Ingredients 

Retinol Emulsion 0.3: Vitamin A Retinol 0.3% a potent ingredient of botanical origin that is highly deliverable to its site of action within skin due to encapsulation with the bio-identical lipids PhosphatidyIcholine and Triglycerides. This well-delivered Retinol also boosts skin health, as it is a vitamin and antioxidant required for normal skin epithelialisation. Vitamin C Ascorbic Acid 0.5% Specially formulated with other ingredients in the formula to be a highly potent cofactor for collagen synthesis. This stabilised, bio-available form of Vitamin C retains all other benefits of the ingredient, including antioxidant activity against environmental stresses, brightening, and protection from photoaging. Bakuchiol 1% A ingredient from the Psoralen Corylifolia (babchi) plant, used for centuries in Ayurvedic medicine to help the appearance of ageing skin. It is even more powerful when combined with Retinol, as it shares the benefits but with higher skin tolerability. Shea Butter 0.8% A skin emollient from the nut of the Karite Tree in West Africa that lessens irritation and soothes skin replenishing gaps between skin cells. It contains fatty acids required by the skin barrier and antioxidants. Tripeptide-1 (Copper Tripeptide-1) 0.5% Clinically proven to stimulate collagen production, which restores the skin's structure and smooths wrinkles over time. Ectoin (Extremozymes) 2% An Extremozyme joining this ingredient pioneered by iS Clinical. Found in several plants thriving in high-salt environments, including the Dead Sea, salty deserts, and marine environments. Shields DNA from environmental stresses. Colloidal Gold Gold complexed into a colloidal form that is biologically usable by the body and participates in collagen synthesis. Sunflower Extract, Rice Bran Extract, Rosemary Leaf Extract A uniquely formulated antioxidant combination functioning as a natural preservative system and potentiator of Retinol activity, increasing its potency by 32%.

Poly-Vitamin Serum: Sodium Hyaluronate (Hyaluronic Acid – Botanically Derived) 40.0% Humectant; demonstrates hydrophilic properties – attracts and binds up to 1800 times its molecular weight in water. Niacinamide (Vitamin B3) 5.0% Promotes microcirculation. Essential for all cells to maintain cellular metabolism (creation of energy necessary for individual cell to perform its function). Saccharum Officinarum (Sugarcane) Extract (Source of Glycolic Acid) 4.0% Desquamation agent that encourages the exfoliation of the stratum corneum. Vaccinium Myrtillus (Bilberry) Fruit/Leaf Extract (Source of Lactic Acid) 1.0% Desquamation agent with moisturising properties; enhances exfoliation of stratum corneum without dehydrating the skin. Pantothenic Acid (Vitamin B5) 1.0% Essential element required for enzymatic functions within all cells. Enables the metabolism of carbohydrates, proteins, and lipids, increasing cellular integrity and efficiency. Tocopherol (Vitamin E) 0.5% Moisturiser and potent lipophilic antioxidant inhibits DNA damage, thymine dimer formation, inflammation, and oxidative damage. Protects against UV-induced photodamage. Retinol (Vitamin A) 0.5% Natural Vitamin A functions as a powerful antioxidant with potent free radical scavenging ability, improves collagen synthesis by favouring biosynthetic activity of fibroblasts and promotes wound healing.

GeneXC Serum: L-Ascorbic Acid (Vitamin C) 20.0% Scientifically advanced, stabilised form of L-Ascorbic Acid providing time-released, continuous delivery. Potent antioxidant with photoprotective and anti-inflammatory properties. Stimulates collagen synthesis and promotes wound healing. Trehalose (Extremozyme) A naturally occurring disaccharide present in a wide variety of plant and animal life, enabling organisms to survive in the harshest climatic conditions. Trehalose is one of the reasons plants like a dry and dormant Resurrection Plant selaginella lepidophylla can ”come back to life” after desert rains. These extremophilic enzymes encourage the mass production of Trehalose, helping to protect the cell structures. Mixed Fruit Acid Extracts Natural fruit and sugar acids that work to enhance desquamation, increase cellular turnover, smooth skin, and decrease fine lines and wrinkles, while enabling deeper penetration of ingredients. Synechococcus Leopoliensis (Extremozyme) A synergistic extremophilic enzyme concentrate from Anacystis Nidulans designed to repair the cell structures damaged by UV radiation. Terminalia Ferdinandiana Fruit (Kakadu Plum) Extract Australian super fruit that yields 100 times the Vitamin C found in an orange. Potent antioxidant that increases collagen and hyaluronic acid production. Boosts skin luminosity, brightens, helps reduce skin redness, and evens skin tone. Plankton Extract - Arginine Ferulate (Extremozyme) Phytoplankton is an ocean plant that has developed extremophilic enzymes which regulate the mitochondrial membrane potential, increase cellular visibility (respiration), help cellular detoxification, and hydrate the epidermis. Hydrolysed Eruca Sativa Leaf Helps to detoxify, strengthen, and repair skin cells. Superoxide Dismutase (SOD) This uniquely designed, natural enzyme safely absorbs harmful free radicals to combat photoaging and cell damage while protecting the skin against future damage. While many non-enzymatic antioxidants are destroyed during antioxidant activity, this version of SOD defends itself and the skin from harmful aggressors that cause skin ageing.

Retinol Emulsion 0.3: Water/Aqua/Eau, Glycerin, Squalane, Pentylene Glycol, Sodium Hyaluronate, Ectoin, Glyceryl Citrate/ Lactate/ Linoleate/ Oleate, Polyglyceryl-4 Cocoate, Polyglyceryl-3 Cocoate, Glyceryl Caprylate, Chlorella Vulgaris Extract, Tocopherol, Butylene Glycol, Bakuchiol, Triethanolamine, Carbomer, Retinol, Phragmites Communis Extract, Poria Cocos Extract, Oryza Sativa (Rice) Bran Extract, Rosmarinus Officinalis (Rosemary) Leaf Extract, Phosphatidylcholine, Propanediol, Butyrospermum Parkii (Shea) Butter, Polysorbate 20, Caprylic/Capric Triglyceride, Lecithin, Lactic Acid, Polysorbate 40, Helianthus Annuus (Sunflower) Extract, Phenoxyethanol, Polyacrylamide, C13-14 Isoalkane, Laureth-7, Tripeptide-1, Dextran, Ascorbic Acid, Colloidal Gold, Glutathione, Panthenol, Heptyl Undecylenate, C13-16 Isoalkane, Dipotassium Glycyrrhizate, Bidens Pilosa Extract, Elaeis Guineensis (Palm) Oil, Gossypium Herbaceum (Cotton) Seed Oil, Linum Usitatissimum (Linseed) Seed Oil, Glycine Soja (Soybean) Extract, Sodium Hydroxide, Disodium EDTA, Phenylpropanol, Ethylhexylglycerin, Caprylyl/ Capryl Glucoside, Diisopropyl Adipate, Triethyl Citrate, Xanthan Gum, Sorbitol, Fragrance/Parfum.

Poly-Vitamin Serum: Water/Aqua/Eau, Sodium Hyaluronate, Niacinamide, Saccharum Officinarum (Sugarcane) Extract [Extrait de canne à sucre], Zinc Sulfate, Pantothenic Acid, Vaccinium Myrtillus Fruit/Leaf Extract, Lysine, Glutamine, PEG-60 Hydrogenated Castor Oil, Polysorbate 20, Camellia Sinensis Leaf Extract, Tocopherol, Retinol, Phenoxyethanol.

GeneXC Serum: Water/Aqua/Eau, Ascorbic Acid, Saccharum Officinarum (Sugarcane) Extract [Extrait de canne à sucre], Trehalose, Glycerin, Hydrolyzed Eruca Sativa Leaf, Pentylene Glycol, Terminalia Ferdinandiana Fruit Extract, Acetyl Tyrosine, Butylene Glycol, Proline, Hydrolyzed Vegetable Protein, Plankton Extract, Citrus Medica Limonum (Lemon) Fruit Extract, Citrus Aurantium Dulcis Fruit Extract, Pyrus Malus (Apple) Fruit Extract, Camellia Sinensis Leaf Extract, Lecithin, Adenosine Triphosphate, Phenoxyethanol, Arginine Ferulate, Ethylbisiminomethylguaiacol Manganese Chloride.

Please note that from time to time, products are innovated without notice. For the most accurate information please consult the product box. 

If you spot an error, please let us know! We will update this ingredients list as soon as possible.


Morning Use, apply 3-4 drops of GeneXC Serum to your hand. Gently dab and smooth the serum over your face and neck using your fingertips. Follow with Poly-Vitamin Serum after cleansing and before moisturising.

Evening Use, apoly 2-3 pumps of Retinol Emulsion 0.3 onto clean skin, covering both the face and neck. Use every 3 days for 3 weeks, and if there are no adverse reactions, increase usage to every 2 days. Alternatively, follow the recommended usage. Moisturise afterwards. Once your skin adjusts to Retinol Emulsion 0.3, incorporate Poly-Vitamin Serum into your routine before or after using Retinol Emulsion and before applying moisturiser.

Pro Tip - Mix 1-2 drops of Poly-Vitamin Serum with your foundation before applying to achieve a dewy glow.

If this product is sealed, please ensure the seal is intact prior to using the product.


All Orders Same Day Dispatch by 2pm M-F (Sydney Business Days) any orders placed after 2pm will leave the following (Sydney Business Day). Please note during big sale periods this can be delayed by a day or two.

FREE Express Shipping for all iS Clinical orders via Australia post.

If it's not right and you haven't opened it yet, you are welcome to Return It within 30 days. Reach out to our team for authorisation prior to returning to us in original sealed condition.

Already opened or used the product? We can only accept returns if product is faulty, not if you dislike the product! please reach out to us first and we can discuss your options as each brand is different. We can help you understand if a return is possible.

We unfortunately cannot accept returns without return authorisation prior to sending to us.

Customer Reviews

Be the first to write a review