iS Clinical Super Serum Advance+
iS Clinical Super Serum Advance+
iS Clinical Super Serum Advance+
iS Clinical Super Serum Advance+
iS Clinical Super Serum Advance+
iS Clinical Super Serum Advance+

iS Clinical

iS Clinical Super Serum Advance+

Sale price$268.00

Or 4 interest-free payments

Zip it now, pay later

4 interest-free payments


Super Serum Advance+ is a scientifically advanced, clinically proven formula that, for the first time, combines a 15% concentration of our next generation L-Ascorbic Acid (Vitamin C) with bioidentical Tripeptide-1 (Copper Tripeptide-1).

This advanced serum, Super Serum Advance+, integrates a clinically proven formula of 15% L-Ascorbic Acid and bioidentical Tripeptide-1 (Copper Tripeptide-1). It also features potent botanical antioxidants and safe skin brighteners. In addition to its remarkable benefits, this serum also aids in diminishing the appearance of hypertrophic (raised) scar tissue and fine stretch marks.

iS Clinical Super Serum Advance+ is suitable for dry, normal, oily, or combination skin, fine lines and wrinkles, scars, fine stretch marks, poor elasticity/thin skin, pre-procedure (use 30 days prior), post-procedure (use after skin has re-epithelialized).

iS Clinical Super Serum Advance+ is suitable during pregnancy or when breastfeeding. Cancer patients in remission may use this product, do not use for patients currently undergoing any active cancer treatments.


This powerful Vitamin C serum is known for its age-defying, super antioxidant and brightening properties. With a lightweight formula and a pH level of 3.0 +/- 0.5, it has been scientifically proven to eliminate dark spots, stimulate collagen production, and reduce fine lines for a radiant, even complexion. Boasting superior protection against environmental aggressors and inflammation, along with natural botanicals for safe and effective brightening results, this serum is clinically proven to increase collagen synthesis and decrease the appearance of lines and wrinkles.

iS Clinical Super Serum Advance+ Benefits:

  • Helps reduce the appearance of fine lines and wrinkles
  • Helps improve the look of hypertrophic (raised) scar tissue and fine stretch marks
  • Safely brightens and helps visibly diminish uneven skin tone
  • Provides support against environmental stressors
  • Provides extremely powerful antioxidant protection
  • Paraben-free


Key Ingredients 

L-Ascorbic Acid (Vitamin C) ADVANCE 0 15.0% Scientifically advanced, stabilised form of L-Ascorbic Acid providing time-released, continuous delivery. Potent antioxidant with photoprotective and anti-inflammatory properties. Stimulates collagen synthesis and promotes wound healing.
 Asiaticoside, Asiatic Acid and Madecassic Acid 
(Centella Asiatica) 0.5% Efficacious antioxidant stimulates collagen synthesis and improves microcirculation, capillary flow, and vascular tone. Promotes wound- healing and reduction of scar tissue.
 Calcium Pantothenate (Vitamin B5) 0.5% Essential element required for enzymatic functions within all cells. Enables the metabolism of carbohydrates, proteins, and lipids, increasing cellular integrity and efficiency.
Arbutin 0.5% Inhibits tyrosinase enzymes that produce melanin, thereby controlling hyperpigmentation. 
Polyporus Umbellatus (Mushroom) Extract 
(Source of Kojic Acid) 0.5% Inhibits tyrosinase enzymes that produce melanin, thereby controlling hyperpigmentation. Also exhibits powerful antibacterial, antimicrobial, and antibiotic properties.
Copper Tripeptide Growth Factor (Bioidentical)
Copper Tripeptide-1 (bioidentical) has been clinically proven to stimulate the synthesis of collagen in skin fibroblasts, and increase accumulation of total proteins, glycosaminoglycans, and DNA in dermal wounds. The Copper Tripeptide-1 sequence is present in collagen and it is suggested that the Copper Tripeptide-1 is released after tissue injury. Copper Tripeptide-1 also increases synthesis of decorin – a small proteoglycan in the regulation of collagen synthesis, wound healing regulation, and anti-tumor defence.

Water/Aqua/Eau, Ascorbic Acid, Hyaluronic Acid, Pentylene Glycol, Arbutin, Polyporus Umbellatus (Mushroom) Extract, Calcium Pantothenate, Zinc Sulfate, Urea, Glucose, Guanidine HCl, Tripeptide-1, Glycerin, Phenoxyethanol, Asiaticoside, Asiatic Acid, Madecassic Acid.

Please note, as the botanical actives in our product can vary seasonally, there may be slight differences in colour, texture, and scent among different batches. Additionally, please note that product innovation may occur without prior notice. For the most precise information, we recommend consulting the product box. 

If you spot an error, please let us know! We will update this ingredients list as soon as possible.


Morning/Evening apply 3-4 drops to the palm of hand. Using fingertips, dab and smooth evenly over face and neck.

If this product is sealed, please ensure the seal is intact prior to using the product.


All Orders Same Day Dispatch by 2pm M-F (Sydney Business Days) any orders placed after 2pm will leave the following (Sydney Business Day). Please note during big sale periods this can be delayed by a day or two.

FREE Express Shipping for all iS Clinical orders via Australia post.

If it's not right and you haven't opened it yet, you are welcome to Return It within 30 days. Reach out to our team for authorisation prior to returning to us in original sealed condition.

Already opened or used the product? We can only accept returns if product is faulty, not if you dislike the product! please reach out to us first and we can discuss your options as each brand is different. We can help you understand if a return is possible.

We unfortunately cannot accept returns without return authorisation prior to sending to us.

Customer Reviews

Based on 2 reviews
Sally Laundess
Really is a super serum

Instantly noticed a difference in hydration and skin texture. Overall skin is more luminous after one week

Naomi Thompson
Excellent vitamin c serum

Repeat buyer of staple product